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Last updated: April 8, 2026

Quick Answer: Generally, taking DGL (deglycyrrhizinated licorice) and slippery elm together is considered safe for most individuals. Both are natural remedies often used for digestive support, particularly for conditions like heartburn and ulcers. However, it's always advisable to consult with a healthcare professional before combining any supplements to ensure no adverse interactions or contraindications exist based on your individual health status and any medications you are taking.

Key Facts

DGL and slippery elm are natural supplements commonly used for digestive health.
Both are known for their demulcent properties, coating and soothing the digestive tract.
Slippery elm forms a gel-like substance when mixed with water, which can protect the stomach lining.
DGL has had the glycyrrhizin removed, which is responsible for the blood pressure-raising side effects of whole licorice.
There are no widely reported significant negative interactions between DGL and slippery elm, but individual responses can vary.

Overview

The question of whether DGL (deglycyrrhizinated licorice) and slippery elm can be taken together is a common one for individuals seeking natural remedies for digestive discomfort. Both DGL and slippery elm have gained popularity for their purported benefits in soothing the gastrointestinal tract and alleviating symptoms associated with conditions like heartburn, acid reflux, gastritis, and ulcers. Their popularity stems from their long history of traditional use and their perceived gentleness compared to pharmaceutical interventions.

Understanding the properties and mechanisms of action of each substance is crucial when considering their combined use. While both are generally considered safe and beneficial for the digestive system, it's important to approach any supplement regimen with a degree of caution and informed awareness. This article will delve into how each works individually, explore their complementary effects, and provide guidance on their combined application, while also highlighting the importance of professional medical advice.

How It Works

DGL (Deglycyrrhizinated Licorice): DGL is a form of licorice root extract where the glycyrrhizin has been removed. Glycyrrhizin is a compound in licorice that can cause adverse effects like increased blood pressure and fluid retention when consumed in large quantities. By removing this component, DGL retains the beneficial properties of licorice for the digestive system without the significant risk of these side effects. DGL is believed to work by stimulating the production of mucus in the stomach and esophagus. This mucus layer acts as a protective barrier against stomach acid, thereby helping to heal and prevent damage to the lining. It can also promote the healing of existing ulcers and reduce inflammation.
Slippery Elm: Slippery elm (Ulmus rubra) is derived from the inner bark of the slippery elm tree. When mixed with water, the inner bark creates a gel-like substance known as mucilage. This mucilage is the primary active component and is highly valued for its demulcent properties. Demulcents are substances that form a protective coating over mucous membranes, providing soothing relief. In the digestive tract, this mucilage can coat the lining of the esophagus, stomach, and intestines, offering protection from irritants and acids. This coating can alleviate symptoms of heartburn, soothe inflammation in the gut, and potentially aid in the healing of ulcers and irritation.
Complementary Actions: The primary benefit of taking DGL and slippery elm together lies in their synergistic effect. Both act as natural protectants and soothers for the digestive lining. DGL works by enhancing the body's natural mucus production, while slippery elm directly provides a protective mucilage coating. This dual action can offer more comprehensive and robust protection for the gastrointestinal tract, potentially leading to faster symptom relief and improved healing for a variety of digestive complaints.
Dosage and Forms: Both DGL and slippery elm are commonly available in chewable tablets, capsules, and powders. Chewable DGL tablets are often recommended to be taken before meals to allow the active compounds to coat the esophagus and stomach as food is consumed. Slippery elm can be prepared as a tea or taken in capsule form. The optimal dosage and timing can vary depending on the specific product and the individual's needs, underscoring the importance of following product instructions or consulting a healthcare provider.

Key Comparisons

Feature	DGL (Deglycyrrhizinated Licorice)	Slippery Elm
Primary Mechanism	Stimulates mucus production to protect lining	Forms a protective mucilage gel coating
Key Benefit	Protects esophagus and stomach lining, aids ulcer healing	Soothes and protects entire GI tract lining, relieves irritation
Traditional Use	Digestive ailments, coughs, sore throats	Digestive ailments, sore throats, wound healing
Potential Side Effects (common form)	Generally well-tolerated; rare mild digestive upset	Generally well-tolerated; rare mild digestive upset
Taste/Texture	Often flavored (e.g., cherry, orange) for chewables	Slightly bitter, can have a somewhat earthy taste

Why It Matters

Symptom Relief for Millions: Digestive issues like heartburn, acid reflux, and ulcers affect a significant portion of the population. According to the American College of Gastroenterology, heartburn is experienced by at least 60 million Americans each month, and up to 20% of the population experiences it weekly. Natural remedies like DGL and slippery elm offer an alternative or complementary approach for individuals seeking to manage these symptoms without or alongside conventional medications.
Gentle Digestive Support: For those who experience side effects from stronger medications or prefer a more natural approach, DGL and slippery elm provide a gentler form of digestive support. Their ability to form protective barriers and soothe inflammation can lead to significant symptom improvement for many, enhancing their quality of life and promoting a healthier gut environment.
Holistic Approach to Gut Health: Integrating these supplements into a broader approach to gut health, which may include dietary adjustments and stress management, can be particularly effective. The combined use of DGL and slippery elm aligns with a holistic perspective on wellness, recognizing the interconnectedness of the digestive system and overall well-being.

In conclusion, while DGL and slippery elm can often be taken together safely and may even offer synergistic benefits for digestive health, it is paramount to consult with a qualified healthcare professional before incorporating them into your routine. They can provide personalized advice, ensure there are no contraindications with your current health conditions or medications, and help you determine the most appropriate dosages and forms for your specific needs, thereby maximizing their benefits while minimizing any potential risks.