What causes kidney pain

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Last updated: April 4, 2026

Quick Answer: Kidney pain is typically caused by issues directly affecting the kidneys, such as infections, stones, blockages, or injuries. It can also be a symptom of conditions affecting the surrounding areas that refer pain to the back, like muscle strain or appendicitis.

Key Facts

What Causes Kidney Pain?

Kidney pain, often felt in the flank (the side of the body between the ribs and the hip), can be a distressing symptom with a variety of underlying causes. Understanding these causes is crucial for seeking appropriate medical attention and treatment. While the kidneys themselves are located deep within the body, protected by the lower ribs and back muscles, pain originating from them or perceived in that area warrants investigation.

Common Causes of Kidney Pain

Kidney Infections (Pyelonephritis)

One of the most common culprits behind kidney pain is a kidney infection, also known as pyelonephritis. This condition occurs when bacteria, often originating from a urinary tract infection (UTI) that has spread upwards to the kidneys, infect one or both kidneys. Symptoms typically include fever, chills, nausea, vomiting, and pain in the flank or lower back. The pain can range from a dull ache to a sharp, intense sensation.

Kidney Stones (Nephrolithiasis)

Kidney stones are solid masses formed from minerals and salts in the urine. When these stones move within the kidney or pass into the ureter (the tube connecting the kidney to the bladder), they can cause excruciating pain. This pain, often called renal colic, is characterized by its sudden onset, severity, and wave-like nature. It typically starts in the flank and can radiate to the groin and abdomen. Associated symptoms may include blood in the urine (hematuria), nausea, vomiting, and frequent urination.

Blockages and Obstructions

Anything that obstructs the normal flow of urine from the kidneys can lead to kidney pain. This includes kidney stones, blood clots, tumors, or external compression of the ureters. When urine cannot drain properly, it backs up into the kidney, causing it to swell. This swelling, known as hydronephrosis, puts pressure on the kidney's structures and nerves, resulting in pain. The pain can be constant or intermittent, depending on the nature and severity of the blockage.

Kidney Injury and Trauma

Direct blows to the back or flank area, such as those sustained in sports injuries, car accidents, or falls, can damage the kidneys. This trauma can lead to bruising, lacerations, or even more severe injuries like kidney rupture. The resulting pain is usually localized to the site of injury and can be accompanied by blood in the urine, swelling, and signs of shock if the bleeding is significant.

Cysts and Tumors

While often asymptomatic, large kidney cysts or tumors can sometimes cause pain by pressing on surrounding tissues or obstructing urine flow. Simple kidney cysts are very common, especially with age, and rarely cause problems. However, complex cysts or cancerous tumors can grow and lead to discomfort, a palpable mass, or blood in the urine.

Glomerulonephritis

This is a group of diseases that cause inflammation and damage to the glomeruli, the tiny filtering units within the kidneys. Glomerulonephritis can be caused by infections, autoimmune diseases (like lupus), or other medical conditions. While some forms are silent, severe inflammation can lead to kidney swelling, pain, and impaired kidney function, sometimes resulting in blood or protein in the urine.

Referred Pain and Other Conditions

It's important to note that pain felt in the back or flank area isn't always directly from the kidneys. This is known as referred pain. Several other conditions can mimic kidney pain:

When to Seek Medical Attention

Any persistent or severe pain in the flank or lower back should be evaluated by a healthcare professional. Seek immediate medical attention if you experience:

A proper diagnosis involves a medical history, physical examination, and potentially diagnostic tests such as urinalysis, blood tests, imaging studies (ultrasound, CT scan, MRI), and urine culture. Early diagnosis and treatment are key to preventing complications and ensuring kidney health.

Sources

  1. Kidney infection - NHSfair-use
  2. Kidney Stones | NIDDKfair-use
  3. Kidney stones - Symptoms and causes - Mayo Clinicfair-use

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