What is axonics therapy

Last updated: April 1, 2026

Quick Answer: Axonics therapy is an FDA-approved neurostimulation treatment using electrical pulses to treat overactive bladder and urinary incontinence. A rechargeable implant stimulates sacral nerves to restore bladder control.

Key Facts

How Axonics Therapy Works

Axonics therapy is a form of sacral neuromodulation that uses electrical stimulation to treat overactive bladder. The system includes a small implanted neurostimulator placed under the skin, typically near the collarbone. The device sends mild electrical pulses to the S3 sacral nerves, which regulate bladder and bowel function, helping to restore normal control and reduce symptoms.

The Implantation Procedure

The implantation is a minimally invasive surgical procedure performed under general or local anesthesia. First, patients undergo a test stimulation trial to determine if the therapy will be effective. If successful, a permanent implant is surgically placed and connected to the sacral nerve. The rechargeable battery lasts 7-10 years and is recharged wirelessly using an external charger, eliminating the need for replacement surgeries.

Conditions Treated

Overactive Bladder (OAB) causes frequent and urgent urination, often disrupting daily life. Urge Incontinence involves involuntary urine leakage when the urge to urinate occurs. These conditions significantly impact quality of life and often don't respond adequately to medications alone. Axonics therapy provides an alternative for patients who haven't achieved desired results with conservative treatments.

Effectiveness and Benefits

Clinical studies demonstrate that Axonics therapy significantly improves symptoms for many patients. Benefits include reduced urinary frequency, decreased episodes of urge incontinence, improved sleep quality, and enhanced quality of life. Many patients reduce or eliminate medication dependence. The therapy is particularly beneficial for patients resistant to conservative treatments like behavioral modifications or antimuscarinergic medications.

Comparison to Alternative Treatments

Traditional treatments include medications, behavioral therapy, and surgical procedures. Medications can cause side effects like dry mouth and constipation. Botox injections offer temporary relief but require repeated procedures. Surgical options like bladder augmentation are more invasive. Axonics therapy provides a middle-ground offering long-term relief through a minimally invasive procedure with the convenience of wireless battery recharging technology.

Related Questions

What causes overactive bladder?

Overactive bladder can result from nerve damage, urinary tract infections, bladder stones, certain medications, or neurological conditions. Sometimes the cause is unknown. Symptoms include frequent urination, sudden urgent urges, and involuntary leakage.

What is sacral nerve stimulation?

Sacral nerve stimulation uses electrical impulses to regulate bladder and bowel function. It stimulates the S3 sacral nerves, which control these functions, helping restore normal control and reduce symptoms of overactive bladder.

What are other treatments for urinary incontinence?

Treatments include pelvic floor exercises, antimuscarinergic medications, behavioral therapy, pessaries, and surgical procedures. Botox injections and catheterization are also options. Axonics therapy is used when other treatments are ineffective.

Sources

  1. Wikipedia - Sacral Neuromodulation CC-BY-SA-4.0
  2. Mayo Clinic - Overactive Bladder All rights reserved