What is pfas

Last updated: April 1, 2026

Quick Answer: PFAS (per- and polyfluoroalkyl substances) are synthetic chemicals used in industrial applications and consumer products that persist indefinitely in the environment and human bodies. These "forever chemicals" are highly resistant to breaking down and are detected in most people's blood worldwide.

Key Facts

What Are PFAS?

Per- and polyfluoroalkyl substances (PFAS) are a group of human-made chemicals containing carbon-fluorine bonds that make them extremely stable and resistant to breaking down. These bonds are among the strongest in chemistry, giving PFAS their remarkable persistence. Scientists have identified thousands of different PFAS chemicals, though only a small fraction have been extensively studied. The most well-known include PFOA and PFOS, which dominated industrial use for decades.

Industrial and Consumer Applications

PFAS chemicals have been used since the 1940s in numerous products and applications:

Environmental and Health Persistence

PFAS earned the nickname "forever chemicals" because they do not break down through natural processes like sunlight, heat, or microbial degradation. Once released into the environment, PFAS persist indefinitely in soil, groundwater, and surface water. Bioaccumulation occurs when PFAS accumulate in living organisms and increase in concentration as they move up the food chain. This persistence means PFAS released decades ago remain present in environmental systems and human bodies today, with concentrations continuing to increase.

Exposure Routes and Detection

The general population is exposed to PFAS through multiple pathways: drinking water contamination, consumption of contaminated food (especially seafood, livestock, and processed foods), food contact materials, household dust, and indoor air. The CDC National Health and Nutrition Examination Survey found PFAS in the blood serum of approximately 97% of Americans, indicating widespread exposure. Occupational exposure affects workers in manufacturing, firefighting, and military settings at higher levels than the general population.

Health Effects and Regulatory Response

Research suggests PFAS exposure may be associated with increased cholesterol levels, liver damage, thyroid disease, decreased vaccine response, kidney and testicular cancer, and reproductive effects. The EPA established drinking water health advisories for PFOA and PFOS in 2022, and various states have set stricter drinking water standards. The FDA began regulating PFAS in food contact materials, though comprehensive regulations continue to evolve. Ongoing research aims to better understand the health impacts of chronic PFAS exposure across populations.

Related Questions

Where are PFAS most commonly found?

PFAS are found in drinking water, food (especially seafood and livestock), non-stick cookware, food packaging, carpeting, textiles, and aqueous film-forming foams at airports and military bases. They persist in landfills and contaminate groundwater through soil infiltration.

How can I reduce PFAS exposure?

Reduce exposure by using activated carbon filters on drinking water, avoiding non-stick cookware, selecting PFAS-free products, consuming less processed food and fast food, and choosing unwrapped fresh produce instead of packaged items whenever possible.

What are current PFAS regulations?

The EPA established health advisories for PFOA and PFOS in drinking water, and many states set stricter standards. The FDA regulates PFAS in food contact materials, while international regulations continue to develop as scientific evidence accumulates.

Sources

  1. EPA - PFAS Information Public Domain
  2. Wikipedia - Persistent Organic Pollutants CC-BY-SA-4.0
  3. NIEHS - Perfluorinated Chemicals Public Domain