What causes fever

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Last updated: April 4, 2026

Quick Answer: Fever is typically caused by your body's immune response to an infection, such as a virus or bacteria. It's a sign that your body is fighting off something harmful, and it's a normal and often beneficial process.

Key Facts

What is a Fever?

A fever, also known as pyrexia, is a temporary increase in your body temperature. It's a common symptom, not an illness itself, and often indicates that your body is fighting off an infection or disease. The average human body temperature is around 98.6°F (37°C), but this can fluctuate slightly throughout the day and vary from person to person. A temperature of 100.4°F (38°C) or higher is generally considered a fever.

Why Does the Body Develop a Fever?

The primary reason your body develops a fever is as a defense mechanism against pathogens. When your body detects harmful invaders like viruses, bacteria, fungi, or other microorganisms, your immune system releases signaling molecules called pyrogens. These pyrogens travel to the hypothalamus, a region in your brain that acts as your body's thermostat. The hypothalamus then signals your body to increase its temperature.

This elevated temperature is thought to have several benefits:

Common Causes of Fever

The vast majority of fevers are caused by infections. Here are some of the most frequent culprits:

Infectious Causes:

Non-Infectious Causes:

While infections are the leading cause, fevers can also arise from other conditions:

When to Seek Medical Advice

While most fevers are harmless and resolve on their own, it's important to know when to consult a healthcare professional. Seek medical advice if:

Understanding the causes of fever can help you manage it effectively and know when to seek professional medical help.

Sources

  1. Fever - WikipediaCC-BY-SA-4.0
  2. Fever in adults - NHSfair-use
  3. Fever - Symptoms and causes - Mayo Clinicfair-use

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